| St. James’ Congregational | Park Road E.U. | |||
| 1807-1811 | John Wilson | |||
| 1822-1835 | Thomas Alexander | |||
| 1835-1838 | John Moir | |||
| 1839-1845 | John Kirk | 1854-1859 | James Bishop Robertson | |
| 1846-1850 | John Hart | 1861-1865 | James Maconachie | |
| 1850-1853 | Patrick Morrison | 1865-1867 | Alexander Wilson | |
| 1854-1858 | Thomas Pullar | 1867-1870 | John Cameron | |
| 1859-1860 | James Proctor | 1871-1874 | Daniel Craig | |
| 1860-1865 | Adam Dunlop | 1875-1877 | Alexander Denholm | |
| 1865-1868 | James Sime, M.A. | 1877-1911 | George Bell, M.A. | |
| 1868-1885 | Daniel Jackson | 1912-1921 | John Murphy, M.A., B.D. | |
| 1885-1906 | William Schofield Thomson | 1922-1925 | Charles Florence | |
| 1906-1925 | John Albert Lees | 1927-1939 | Willam Gaylor | |
| 1925-1928 | Harry Bedford | 1940-1947 | Douglas Mackenzie Gordon, M.A. | |
| 1928-1948 | Thomas Baillie | 1948-1952 | John Innes | |
| 1948-1957 | Hector Ross, M.A. | 1953-1956 | George Kirk | |
| 1958-1965 | Leonard Sykes | 1957-1966 | Stanley M. Britton | |
1966 – the Churches merge to form Hamilton Congregational Church.
| 1966-1971 | Stanley M. Britton | |
| 1972-1977 | Sam Jones | |
| 1977-1982 | William Miller | |
| 1984-1989 | Ken Forbes | |
| 1989-2008 | Gordon W. Smith | |
| 2010-2014 | Derek G Corner, B.Sc., P.G.C.E.(S). | |
| February 2017 – | Lindsey Sanderson, M.A., B.D. |
On 1st April 2000 the Church with many others became part of the Scottish Synod of the United Reformed Church.